Early Diagnosis and Management of Extracranial Carotid Vasculopathy in Mitigating Neurological Complications of Sickle Cell Disease

نویسندگان

  • Sri Hari Sundararajan
  • Sudipta Roychowdhury
  • Naiem Nassiri
  • Beth Savage
  • Richard Drachtman
چکیده

While cerebral vasculopathy is a well-known early complication of sickle cell disease that has warranted transcranial doppler surveillance, little has been documented regarding the role of cervical circulation in the development of cerebrovascular events and transient ischemic attacks amongst sickle cell patients. We present the unique case of a symptomatic 18-year-old male with sickle cell disease found to have critical cervical carotid stenosis in the absence of significant intracranial vasculopathy. Increased awareness of the potential role of the extracranial circulation in the development of sickle cell related cerebrovascular events is warranted.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Extracranial internal carotid arterial disease in children with sickle cell anemia.

BACKGROUND Sickle cell anemia is one of the commonest causes of stroke in children. It is usually, but not always, associated with intracranial vasculopathy. We have assessed the value of ultrasound screening for extracranial internal carotid artery disease. DESIGN AND METHODS Using Doppler ultrasound scanning, we assessed peak systolic blood velocity, tortuosity and stenosis in the extracran...

متن کامل

خودکارآمدی بیماران سلول‌داسی‌شکل بعد از دریافت آموزش مبتنی بر برنامه خودمدیریتی (24 هفته پیگیری)

Background: Patients with sickle cell disease suffer from various complications during their lifetime and have to adapt themselves to this chronic disease through promoting their self-management and preventing complications of the disease. Chronic disease self-management programs are a combination of strategies that increase self-efficacy and promote self-management behaviors. The present study...

متن کامل

The Effectiveness of self management program on quality of life in patients with sickle cell disease

Background Sickle cell patients suffer from many physical, psychological, and social problems that can affect their quality of life. To deal with this chronic condition and manage their disease and prevent complications associated with the disease, they must learn skills and behaviours. The aim of this study was to determine the effectiveness of self-management programs on quality of life in t...

متن کامل

The Influence of Fetal Hemoglobin on Clinical and Hematological Variables of Children and Adolescents with Sickle Cell Anemia in Basra, Southern Iraq

Background: There are many parameters that modulate the severity of sickle cell anemia. Fetal hemoglobin (Hb F) is one of these major variables. However, its effect is clinically inconsistent. We conducted a descriptive study to assess the influence of Hb F on clinical events and hematological variables in patients with sickle cell anemia. Methods: 151 patients with sickle cell anemia with a st...

متن کامل

Vascular Disease: Diagnostic and Therapeutic Approaches.

vascular disease diagnostic and therapeutic approaches peripheral vascular disease basic diagnostic and peripheral vascular disease basic diagnostic and peripheral vascular diseasebasic diagnostic and vascular disease diagnostic and therapeutic approaches vascular disease diagnostic and therapeutic approaches peripheral vascular disease: basic diagnostic and nanomedicine approaches in vascular ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2015